Mouse Galectin-1 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse Galectin-1 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Lgals1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Galectin-1 DuoSet ELISA, 15 Plate

• 14 kDa laminin-binding protein
• 14 kDa lectin
• Beta-galactoside-binding lectin L-14-I
• BHL
• DKFZp686E23103
• GAL1
• gal-1
• Galaptin
• galectin 1
• Galectin1
• Galectin-1
• GBP
• HBL
• HLBP14
• HPL
• L-14
• Lactose-binding lectin 1
• Lectin galactoside-binding soluble 1
• lectin, galactoside-binding, soluble, 1
• LGALS1
• Putative MAPK-activating protein PM12
• S-Lac lectin 1

Background

The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Publications for Galectin-1 (DY1245)(10)

Publications using DY1245

• SS Kim, JB Harford, M Moghe, C Doherty, EH Chang A Novel P53 Nanomedicine Reduces Immunosuppression and Augments Anti-PD-1 Therapy for Non-Small Cell Lung Cancer in Syngeneic Mouse Models Cells, 2022-10-31;11(21):. 2022-10-31 [PMID: 36359830] (Mouse)
• SO Vasudevan, AJ Russo, P Kumari, SK Vanaja, VA Rathinam A TLR4-independent critical role for CD14 in intracellular LPS sensing Cell Reports, 2022-05-03;39(5):110755. 2022-05-03 [PMID: 35508125] (Mouse)
• P Kumari, AJ Russo, SS Wright, S Muthupalan, VA Rathinam Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense Cell Reports, 2021-04-20;35(3):109012. 2021-04-20 [PMID: 33882312] (Mouse)
• HL Law, RD Wright, AJ Iqbal, LV Norling, D Cooper A Pro-resolving Role for Galectin-1 in Acute Inflammation Front Pharmacol, 2020-03-20;11(0):274. 2020-03-20 [PMID: 32265698] (Mouse)
• JM Lykken, M Horikawa, V Minard-Col, M Kamata, T Miyagaki, JC Poe, TF Tedder Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms Blood, 2016-02-17;127(15):1886-95. 2016-02-17 [PMID: 26888257] (Mouse)
• Van Ry P, Wuebbles R, Key M, Burkin D Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy. Mol Ther, 2015-06-08;23(8):1285-97. 2015-06-08 [PMID: 26050991] (Mouse)
• Al-Salam S, Hashmi S Galectin-1 in early acute myocardial infarction. PLoS ONE, 2014-01-31;9(1):e86994. 2014-01-31 [PMID: 24498007] (Mouse)
• Xie , C, Du , Y, Kumar , K, Li , L, Han , J, Liu , K, Zhou , X J, Mohan , C Lupus-prone strains vary in susceptibility to antibody-mediated end organ disease. Genes Immun, 2013-02-07;14(3):170-8. 2013-02-07 [PMID: 23392277] (Mouse)
• Pitteri SJ, Kelly-Spratt KS, Gurley KE Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. Cancer Res., 2011-06-08;71(15):5090-100. 2011-06-08 [PMID: 21653680] (Mouse)
• Tsai CM, Chiu YK, Hsu TL, Lin IY, Hsieh SL, Lin KI Galectin-1 promotes immunoglobulin production during plasma cell differentiation. J. Immunol., 2008-10-01;181(7):4570-9. 2008-10-01 [PMID: 18802059] (Mouse)

FAQs for Galectin-1 (DY1245). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Lgals1