Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit

Images

 

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit Summary

Background
The Quantikine Mouse BAFF/BLyS Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse BAFF/BLyS in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse BAFF/BLyS and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse BAFF/BLyS ...showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse BAFF/BLyS.
Show More
Specificity
Natural and recombinant mouse BAFF/BLyS
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Tnfsf13b

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Interference observed with 1 or more available related molecules.
Publications
Read Publications using MBLYS0.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit

  • ApoL related ligand TALL-1
  • B lymphocyte stimulator
  • BAFF
  • BAFFB-cell activating factor
  • B-cell-activating factor
  • BLyS
  • BLYSB-lymphocyte stimulator
  • CD257 antigen
  • CD257
  • Dendritic cell-derived TNF-like molecule
  • DTL
  • TALL1
  • TALL-1delta BAFF
  • TALL1Delta4 BAFF
  • THANK
  • TNF- and APOL-related leukocyte expressed ligand 1
  • TNF and ApoL-related leukocyte expressed ligand 1
  • TNF homolog that activates apoptosis
  • TNFSF13B
  • TNFSF20
  • tumor necrosis factor (ligand) superfamily, member 13b
  • tumor necrosis factor (ligand) superfamily, member 20
  • tumor necrosis factor ligand superfamily member 13B
  • tumor necrosis factor superfamily, member 13b
  • tumor necrosis factor-like protein ZTNF4
  • ZTNF4

Background

BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

Customers Who Viewed This Item Also Viewed...

210-TA/CF
Species: Hu
Applications: BA
DY884B
Species: Hu
Applications: ELISA
NB100-56516
Species: Hu, Mu
Applications: IHC, IHC-P, WB
AF1162
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut, WB
AF193
Species: Hu
Applications: Block, CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ELISA(Sta), ELISA, Flow, WB
D6050
Species: Hu
Applications: ELISA
DY417
Species: Mu
Applications: ELISA
NBP2-29323
Species: Bv, Ca, Ch, Hu, Mu, Rt, Xp
Applications: Func-Inh
DDX0131P-100
Species: Hu
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
DCDL40
Species: Hu
Applications: ELISA
NBP1-43435
Species: Hu, Mu
Applications: Flow, WB
NBP2-37585
Species: Hu, Mu
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, WB
AF3589
Species: Hu, Mu, Rt
Applications: ICC, Simple Western, WB
6507-IL/CF
Species: Hu
Applications: BA
AF5129
Species: Hu
Applications: WB
202-IL/CF
Species: Hu
Applications: BA
NBP2-25196
Species: Hu, Mu
Applications: CyTOF-ready, Flow, ICC/IF, In vitro, WB
7268-CT
Species: Hu
Applications: BA
NBP2-67309
Species: Hu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, IP, WB
MBLYS0
Species: Mu
Applications: ELISA
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for BAFF/BLyS/TNFSF13B (MBLYS0)(26)

We have publications tested in 1 confirmed species: Mouse.


Filter By Application
All Applications
Filter By Species
Mouse
(26)
All Species
Showing Publications 1 - 10 of 26. Show All 26 Publications.
Publications using MBLYS0 Applications Species
SH Khiew, D Jain, J Chen, J Yang, D Yin, JS Young, A Dent, R Sciammas, ML Alegre, AS Chong Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells J. Clin. Invest., 2020;0(0):. 2020 [PMID: 32452834] (Mouse) Mouse
MR Edwards, R Dai, B Heid, C Cowan, SR Werre, T Cecere, SA Ahmed Low-dose 17&alpha-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice Sci Rep, 2020;10(1):5210. 2020 [PMID: 32251357] (Mouse) Mouse
Y Nakamura, M Abe, K Kawasaki, T Miyake, T Watanabe, O Yoshida, M Hirooka, B Matsuura, Y Hiasa Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease Sci Rep, 2019;9(1):977. 2019 [PMID: 30700810] (Mouse) Mouse
AS Wilhelmson, M Lantero Ro, A Stubelius, P Fogelstran, I Johansson, MB Buechler, S Lianoglou, VN Kapoor, ME Johansson, JB Fagman, A Duhlin, P Tripathi, A Camponesch, BT Porse, AG Rolink, H Nissbrandt, SJ Turley, H Carlsten, IL Mårtensson, MCI Karlsson, Å Tivesten Testosterone is an endogenous regulator of BAFF and splenic B cell number Nat Commun, 2018;9(1):2067. 2018 [PMID: 29802242] (Mouse) Mouse
W Alturaiki, AJ McFarlane, K Rose, R Corkhill, PS McNamara, J Schwarze, BF Flanagan Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection Cytokine, 2018;0(0):. 2018 [PMID: 29396045] (Mouse) Mouse
LH Thai, S Le Gallou, A Robbins, E Crickx, T Fadeev, Z Zhou, N Cagnard, J Mégret, C Bole, JC Weill, CA Reynaud, M Mahévas BAFF and CD4T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context Blood, 2018;0(0):. 2018 [PMID: 29378696] (Mouse) Mouse
KM Azzam, JH Madenspach, DW Cain, L Lai, KM Gowdy, P Rai, K Janardhan, N Clayton, W Cunningham, H Jensen, PS Patel, JF Kearney, GA Taylor, MB Fessler Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces JCI Insight, 2017;2(16):. 2017 [PMID: 28814662] (Mouse) Mouse
S Sanges, M Jendoubi, N Kavian, C Hauspie, S Speca, JC Crave, T Guerrier, G Lefèvre, V Sobanski, A Savina, E Hachulla, PY Hatron, M Labalette, F Batteux, S Dubucquoi, D Launay B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis Front Immunol, 2017;8(0):53. 2017 [PMID: 28223983] (Mouse) Mouse
FM Verhamme, LJ Seys, EG De Smet, S Provoost, W Janssens, D Elewaut, GF Joos, GG Brusselle, KR Bracke Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure Mucosal Immunol, 2017;0(0):. 2017 [PMID: 28145442] (Mouse) Mouse
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity Cell, 2016;0(0):. 2016 [PMID: 27523608] (Mouse) Mouse
Show All 26 Publications.

Reviews for BAFF/BLyS/TNFSF13B (MBLYS0) (0)

There are no reviews for BAFF/BLyS/TNFSF13B (MBLYS0). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for BAFF/BLyS/TNFSF13B (MBLYS0) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional BAFF/BLyS/TNFSF13B Products

Bioinformatics Tool for BAFF/BLyS/TNFSF13B (MBLYS0)

Discover related pathways, diseases and genes to BAFF/BLyS/TNFSF13B (MBLYS0). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for BAFF/BLyS/TNFSF13B (MBLYS0)

Discover more about diseases related to BAFF/BLyS/TNFSF13B (MBLYS0).
 

Pathways for BAFF/BLyS/TNFSF13B (MBLYS0)

View related products by pathway.

PTMs for BAFF/BLyS/TNFSF13B (MBLYS0)

Learn more about PTMs related to BAFF/BLyS/TNFSF13B (MBLYS0).

Blogs on BAFF/BLyS/TNFSF13B

There are no specific blogs for BAFF/BLyS/TNFSF13B, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit and receive a gift card or discount.

Bioinformatics

Gene Symbol Tnfsf13b