Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit



Product Details

Reactivity MuSpecies Glossary
Applications ELISA

Order Details

Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit Summary

The Quantikine Mouse BAFF/BLyS Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse BAFF/BLyS in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse BAFF/BLyS and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse BAFF/BLyS ...showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse BAFF/BLyS.
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Natural and recombinant mouse BAFF/BLyS
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
Interference observed with 1 or more available related molecules.
Read Publications using MBLYS0.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse BAFF/BLyS/TNFSF13B Quantikine ELISA Kit

  • ApoL related ligand TALL-1
  • B lymphocyte stimulator
  • BAFF
  • BAFFB-cell activating factor
  • B-cell-activating factor
  • BLyS
  • BLYSB-lymphocyte stimulator
  • CD257 antigen
  • CD257
  • Dendritic cell-derived TNF-like molecule
  • DTL
  • TALL1
  • TALL-1delta BAFF
  • TALL1Delta4 BAFF
  • TNF- and APOL-related leukocyte expressed ligand 1
  • TNF and ApoL-related leukocyte expressed ligand 1
  • TNF homolog that activates apoptosis
  • TNFSF13B
  • TNFSF20
  • tumor necrosis factor (ligand) superfamily, member 13b
  • tumor necrosis factor (ligand) superfamily, member 20
  • tumor necrosis factor ligand superfamily member 13B
  • tumor necrosis factor superfamily, member 13b
  • tumor necrosis factor-like protein ZTNF4
  • ZTNF4


BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for BAFF/BLyS/TNFSF13B (MBLYS0)(26)

We have publications tested in 1 confirmed species: Mouse.

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Showing Publications 1 - 10 of 26. Show All 26 Publications.
Publications using MBLYS0 Applications Species
SH Khiew, D Jain, J Chen, J Yang, D Yin, JS Young, A Dent, R Sciammas, ML Alegre, AS Chong Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells J. Clin. Invest., 2020;0(0):. 2020 [PMID: 32452834] (Mouse) Mouse
MR Edwards, R Dai, B Heid, C Cowan, SR Werre, T Cecere, SA Ahmed Low-dose 17&alpha-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice Sci Rep, 2020;10(1):5210. 2020 [PMID: 32251357] (Mouse) Mouse
Y Nakamura, M Abe, K Kawasaki, T Miyake, T Watanabe, O Yoshida, M Hirooka, B Matsuura, Y Hiasa Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease Sci Rep, 2019;9(1):977. 2019 [PMID: 30700810] (Mouse) Mouse
AS Wilhelmson, M Lantero Ro, A Stubelius, P Fogelstran, I Johansson, MB Buechler, S Lianoglou, VN Kapoor, ME Johansson, JB Fagman, A Duhlin, P Tripathi, A Camponesch, BT Porse, AG Rolink, H Nissbrandt, SJ Turley, H Carlsten, IL Mårtensson, MCI Karlsson, Å Tivesten Testosterone is an endogenous regulator of BAFF and splenic B cell number Nat Commun, 2018;9(1):2067. 2018 [PMID: 29802242] (Mouse) Mouse
W Alturaiki, AJ McFarlane, K Rose, R Corkhill, PS McNamara, J Schwarze, BF Flanagan Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection Cytokine, 2018;0(0):. 2018 [PMID: 29396045] (Mouse) Mouse
LH Thai, S Le Gallou, A Robbins, E Crickx, T Fadeev, Z Zhou, N Cagnard, J Mégret, C Bole, JC Weill, CA Reynaud, M Mahévas BAFF and CD4T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context Blood, 2018;0(0):. 2018 [PMID: 29378696] (Mouse) Mouse
KM Azzam, JH Madenspach, DW Cain, L Lai, KM Gowdy, P Rai, K Janardhan, N Clayton, W Cunningham, H Jensen, PS Patel, JF Kearney, GA Taylor, MB Fessler Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces JCI Insight, 2017;2(16):. 2017 [PMID: 28814662] (Mouse) Mouse
S Sanges, M Jendoubi, N Kavian, C Hauspie, S Speca, JC Crave, T Guerrier, G Lefèvre, V Sobanski, A Savina, E Hachulla, PY Hatron, M Labalette, F Batteux, S Dubucquoi, D Launay B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis Front Immunol, 2017;8(0):53. 2017 [PMID: 28223983] (Mouse) Mouse
FM Verhamme, LJ Seys, EG De Smet, S Provoost, W Janssens, D Elewaut, GF Joos, GG Brusselle, KR Bracke Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure Mucosal Immunol, 2017;0(0):. 2017 [PMID: 28145442] (Mouse) Mouse
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity Cell, 2016;0(0):. 2016 [PMID: 27523608] (Mouse) Mouse
Show All 26 Publications.

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Gene Symbol Tnfsf13b