MOS Antibody (R38.1) [DyLight 755]

• Reactivity: Xp
• Applications: WB, ELISA
• Clone: R38.1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 755

MOS Antibody (R38.1) [DyLight 755] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: MBP-MOS fusion protein.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: MOS
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-2739. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MOS Antibody (R38.1) [DyLight 755]

• c-mos
• EC 2.7.11
• EC 2.7.11.1
• MGC119962
• MGC119963
• MSV
• oncogene MOS, Moloney murine sarcoma virus
• Oocyte maturation factor mos
• Proto-oncogene c-Mos
• proto-oncogene serine/threonine-protein kinase mos
• v-mos Moloney murine sarcoma viral oncogene homolog

Background

MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MOS