Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Bv
Applications: WB
Host: Rabbit Polyclonal
Species: Xp
Applications: WB, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
4342 |
Alternate Names |
- c-mos
- EC 2.7.11
- EC 2.7.11.1
- MGC119962
- MGC119963
- MSV
- oncogene MOS, Moloney murine sarcoma virus
- Oocyte maturation factor mos
- Proto-oncogene c-Mos
- proto-oncogene serine/threonine-protein kinase mos
- v-mos Moloney murine sarcoma viral oncogene homolog
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Research Areas for MOS
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication