Human MMRN2 - Ready-To-Use ELISA Kit (Colorimetric)

ELISA: Human MMRN2 - Ready-To-Use ELISA Kit (Colorimetric) [NBP3-39508] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids
• Standard Curve Range: 78.1 - 5000 pg/mL (example only; lot dependent)
• Sensitivity: 33 pg/mL (example only; lot dependent)

Human MMRN2 - Ready-To-Use ELISA Kit (Colorimetric) Summary

• Description: The Ready-To-Use ELISA kit offers pre-diluted detection reagents and a shorter experimental time.
  Assay Length: 3 hours
• Standard Curve Range: 78.1 - 5000 pg/mL (example only; lot dependent)
• Sensitivity: 33 pg/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 12 (example only; lot dependent)
• Intra-Assay: %CV < 10 (example only; lot dependent)
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: MMRN2

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human MMRN2 - Ready-To-Use ELISA Kit (Colorimetric)

• Elastin microfibril interface located protein 3
• Elastin microfibril interfacer 3EMILIN-3
• EMILIN3
• EMILIN-like protein EndoGlyx-1
• EndoGlyx-1 p125/p140 subunit
• Endoglyx-1
• FLJ13465
• MMRN2
• multimerin 2
• multimerin-2

Background

The MMRN2 gene encodes a 949 amino acid long, 104 kDA multimerin-2 protein that prevents endothelial cells motility. The elastic microfibril interface-located (EMILIN) protein family is an extracellular matrix glycoprotein. Additionally, this protein acts as a negative regulator of angiogenesis by downregulating activation by binding VEGFA. MMRN2 has been linked to adenocarcinoma and skin cancer as it participates in MAPK signaling, PTEN pathway, transendothelial migration of leukocytes, and UPA-UPAR pathway. It has been known to interact with genes VDR, MAPK7, MAP3K3, and DAXX.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: MMRN2