MMP-9 Antibody

Images

 
Western Blot: MMP-9 Antibody [NBP1-39597] - Analysis of anti-MMP-9 antibody with mouse liver tissue lysate.
Immunohistochemistry-Paraffin: MMP-9 Antibody [NBP1-39597] - Analysis of anti-MMP-9 antibody with human spleen, neutrophils at concentration 5 ug/ml.

Product Details

Summary
Reactivity Hu, Eq, Mk, Pm, RbSpecies Glossary
Applications WB, ELISA, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

MMP-9 Antibody Summary

Immunogen
Synthetic peptide from human MMP9.
Specificity
KLH conjugated synthetic peptide comprising amino acids 659 - 674 [LDTHDVFQYREKAYFC] of the human matrix metalloproteinase 9 (MMP9) protein.
Predicted Species
Rabbit (93%), Primate (100%), Equine (93%), Monkey (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MMP9
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:500
  • ELISA 1:1000
  • Immunohistochemistry-Paraffin 5 ug/ml
Positive Control
Artery Lysate (NB820-60569)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%), Elephant (93%), Canine (80%), Porcine (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for MMP-9 Antibody

  • 92 kDa gelatinase
  • 92 kDa type IV collagenase
  • CLG4B
  • EC 3.4.24
  • EC 3.4.24.35
  • Gelatinase B
  • GELB
  • macrophage gelatinase
  • MANDP2
  • matrix metallopeptidase 9
  • matrix metalloproteinase 9
  • matrix metalloproteinase-9
  • MMP9
  • MMP-9
  • type V collagenase

Background

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGF beta and proTNF alpha. MMP9 contributes to the invasion and metastasis of various human malignancies. Clone F37P4A3 has been shown to be useful for western blotting, immunoflorence staining and immunohistochemistry of human, rabbit, dog, and pig acetylated MMP9.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MMP9
Entrez
Uniprot