MMP-7 Antibody (6A4) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 6A4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

MMP-7 Antibody (6A4) [mFluor Violet 450 SE] Summary

• Immunogen: Human MMP-7 synthetic peptide
  AEYSLFPNSPKWTSKV, Ala93-Val108
  Accession # P09237
• Specificity: Detects recombinant human (rh) Pro-MMP-7 (aa 18-267) in Western blots. In Western blots, no cross-reactivity with rhMMP-1, rhMMP-2, rhMMP-9 or mature rhMMP-7 (aa 95-267) is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MMP7
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from ascites

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MMP-7 Antibody (6A4) [mFluor Violet 450 SE]

• EC 3.4.24
• EC 3.4.24.23
• Matrilysin
• matrin
• matrix metallopeptidase 7 (matrilysin, uterine)
• matrix metalloproteinase 7 (matrilysin, uterine)
• Matrix metalloproteinase-7
• MMP7
• MMP-7
• MPSL1
• Pump-1 protease
• PUMP1
• PUMP-1
• uterine matrilysin
• Uterine metalloproteinase

Background

MMP7 is a Metallopeptidase M10A type protease. MMP-7 (Matrilysin) is constitutively produced by exocrine epithelial cells through out the body. It is capable of degrading casein, fibronectin, gelatins of types 1, III, IV, and V, in addition to activating procollagenase. It has been shown to play a key role in invasion by carcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MMP7