MMP-19 Peptide

Product Discontinued

MMP-19 Peptide Summary

• Immunogen: This protein is not active and should not be used for experiments requiring activity.
• Protein/Peptide Type: Peptide
• Gene: MMP19

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
• Application Notes: This peptide is useful as a blocking peptide for PAB4786.
  This product may contain endotoxins and is not suitable for use with live cells.
  
  For further blocking peptide related protocol, click here.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized with 100% acetonitrile. Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MMP-19 Peptide

• EC 3.4.24.-
• matrix metallopeptidase 19
• matrix metalloproteinase 18
• matrix metalloproteinase 19
• Matrix metalloproteinase RASI
• Matrix metalloproteinase-18
• matrix metalloproteinase-19
• MMP-18
• MMP18MMP-19
• MMP19
• MMP-19
• RASI
• RASI-1

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and it has a role in cellular proliferation as well as migration and adhesion to type I collagen. Multiple transcript variants encoding distict isoforms have been identified for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Publications for MMP-19 Peptide (P1810)(1)

Publication using P1810

• Yu G, Herazo-Maya JD, Nukui T et al. Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer. Am. J. Respir. Crit. Care Med. 2014-09-24 [PMID: 25250855]

Bioinformatics

• Gene Symbol: MMP19