MKK7/MEK7 Antibody

Images

 
Western Blot: MEK7 Antibody [NBP2-17272] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: MEK7 Antibody [NBP2-17272] - Immunohistochemical analysis of paraffin-embedded adenocarcinoma, using antibody at 1:250 dilution.

Product Details

Summary
Reactivity Hu, Mu, Rt, Sh, XpSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MKK7/MEK7 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human MEK7. The exact sequence is proprietary.
Localization
Nucleus; Cytoplasm
Predicted Species
Rat (99%), Sheep (99%), Xenopus (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAP2K7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (92%), Zebrafish (88%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol, 1% BSA
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for MKK7/MEK7 Antibody

  • c-Jun N-terminal kinase kinase 2
  • dual specificity mitogen-activated protein kinase kinase 7
  • EC 2.7.12.2
  • JNK kinase 2
  • JNK-activating kinase 2
  • JNKK 2
  • JNKK2
  • MAP kinase kinase 7
  • MAP2K7
  • MAPK/ERK kinase 7
  • MAPKK7
  • MEK 7
  • MEK7
  • mitogen-activated protein kinase kinase 7
  • MKE7
  • MKK7
  • MKK7MAPKK 7
  • PRKMK7

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol MAP2K7
Uniprot
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