MGST2 Antibody [Alexa Fluor™ Plus 555]

Product Discontinued

MGST2 Antibody [Alexa Fluor™ Plus 555] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human MGST2 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MGST2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MGST2 Antibody [Alexa Fluor™ Plus 555]

• EC 2.5.1.18
• FLJ27438
• GST2MGC14097
• MGST-II
• microsomal glutathione S-transferase 2
• Microsomal GST-2
• Microsomal GST-II
• truncated microsomal glutathione S-transferase 2

Background

Characterized as important mediators of inflammation, MGST2 (microsomal glutathione S-transferase 2) is an important regulator of leukotriene and glutathione. MGST2 belongs to the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family of six human proteins. Several of these proteins are involved in the creation of leukotrienes and prostaglandin E. MGST2 catalyzes the production of LTC4 from LTA4 and reduced glutathione, and also catalyzes the conjugation of 1-chloro-2, 4-dinitrobenzene with reduced glutathione. Diseases associated with this gene include psoriasis, asthma, leukemia, prostatitis, breast cancer and progressive familial intrahepatic cholestasis type 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MGST2