MFNG Antibody Blocking Peptide

Product Discontinued

MFNG Antibody Blocking Peptide Summary

• Description: A human MFNG antibody blocking peptide.

  Source: Synthetic

  (Accession #: NP_002396)
  
  For longer periods of storage, aliquot and store at -20C. Avoid repeat freeze-thaw cycles.

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: MFNG
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
  • Western Blot
• Application Notes: This peptide is useful as a blocking peptide for NBP1-79289. This synthetic peptide is designed for use in an antibody competition assay with its corresponding antibody. Use of this product in any other assay has not yet been tested.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized with sterile distilled water.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: N/A
• Reconstitution Instructions: Reconstitute with 100ul of sterile PBS for a final peptide concentration of 1 mg/ml.

Alternate Names for MFNG Antibody Blocking Peptide

• beta-1,3-N-acetylglucosaminyltransferase manic fringe
• EC 2.4.1.222
• manic fringe (Drosophila) homolog
• manic fringe homolog (Drosophila)
• MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
• MFNG
• O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Background

MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: MFNG