Melusin/ITGB1BP2 Antibody [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

Melusin/ITGB1BP2 Antibody [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human Melusin
  Ser2-Glu347
  Accession # Q9UKP3
• Specificity: Detects human Melusin in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Melusin/ITGB1BP2 Antibody [Alexa Fluor® 405]

• CHORDC3
• integrin beta 1 binding protein (melusin) 2
• integrin beta-1-binding protein 2
• ITGB1BP
• ITGB1BP2
• Melusin
• MGC119214

Background

Melusin is a 38 kDa cytoplasmic protein that interacts specifically with the cytoplasmic domain of the beta 1 integrin subunit. It is expressed solely in striated muscle where it detects mechanical stress. The 347 amino acid residue human Melusin contains two amino terminal cysteine-rich repeats that are separated by an intervening sequence at the extreme carboxy-terminal. Melusin has a stretch of negatively charged residues (aspartic and glutamic acids). Human Melusin shares 93%, 92% and 96% amino acid sequence homology with rat, mouse and canine Melusin, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.