Melatonin R1A/MT1/MTNR1A Antibody

Images

 
Western Blot: Melatonin R1A/MT1/MTNR1A Antibody [NBP1-28912] - Staining of Rat Retina lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour.Detected by chemiluminescence.

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Melatonin R1A/MT1/MTNR1A Antibody Summary

Immunogen
Peptide with sequence C-SLKYDKLYSSKNS corresponding to internal region according to NP_005949.1.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MTNR1A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.3 - 1 ug/ml
  • Peptide ELISA Detection limit 1:6000
Application Notes
WB: Approx. 45 kDa band observed in KELLY lysate (calculated MW of 39.4 kDa band according to NP_005949.1).
Publications
Read Publications using NBP1-28912.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Mouse, Dog, Cow

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris (pH 7.3), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Melatonin R1A/MT1/MTNR1A Antibody

  • Mel1a receptor
  • Mel-1A-R
  • Melatonin R1A
  • melatonin receptor 1A
  • melatonin receptor type 1A
  • MelatoninR1A
  • MT1
  • MTNR1A

Background

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Melatonin R1A/MT1/MTNR1A Antibody (NBP1-28912)(4)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Melatonin R1A/MT1/MTNR1A Antibody (NBP1-28912). (Showing 1 - 3 of 3 FAQs).

  1. I saw that you have the antibodies for the both receptors of melatonin but not listed with FACS application. I need more information about what is better for my assay.
    • At this time, none of our melatonin receptor antibodies have been tested and validated in Flow. Should you choose to purchase and test one of them, you would qualify for the Innovator's Rewards program. You should take a look at each individual antibody, the clonality, conjugates, immunogen region and all relevant data in order to decide which product would be most suitable for your needs.
  2. Do you have MTNR1A polyclonal antibody ?
    • We have two antibodies to MTNR1A that are polyclonal: http://www.novusbio.com/productsearch?keys=MTNR1A%20&fq[category]=Primary%2BAntibodies
  3. Do you have MTNR1A polyclonal antibody ?
    • We have three antibodies to MTNR1A that are polyclonal: http://www.novusbio.com/productsearch?keys=MTNR1A%20&fq[category]=Primary%2BAntibodies

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MTNR1A
Entrez
Uniprot