MEKK4 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 500 SE

MEKK4 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 75 to 125 of human Mitogen-Activated Protein Kinase Kinase Kinase 4 using the numbering given in entry NP_005913.2 (GeneID 4216).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAP3K4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MEKK4 Antibody [mFluor Violet 500 SE]

• EC 2.7.11.25
• FLJ42439
• MAPKKK4yeast, homolog of
• MEKK 4
• mitogen-activated protein kinase kinase kinase 4

Background

MEK kinase 4 (MEKK4), also known as MTK1, is a Ser/Thr protein kinase belonging to the MAP kinase kinase kinase family (1). This protein contains a protein kinase catalytic domain at the C-terminus. The N-terminal, non-kinase domain may contain a regulatory domain. MEKK4 regulates p38 and JNK, butnot ERK pathway, through the phosphorylation of the MAP2Ks MKK3 and MKK6 and MKK4 and MKK7 respectively (1-2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAP3K4