Species: Hu, Rt
Applications: WB, ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
MEK kinase 4 (MEKK4), also known as MTK1, is a Ser/Thr protein kinase belonging to the MAP kinase kinase kinase family (1). This protein contains a protein kinase catalytic domain at the C-terminus. The N-terminal, non-kinase domain may contain a regulatory domain. MEKK4 regulates p38 and JNK, butnot ERK pathway, through the phosphorylation of the MAP2Ks MKK3 and MKK6 and MKK4 and MKK7 respectively (1-2).
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
4216 |
Alternate Names |
- EC 2.7.11.25
- FLJ42439
- MAPKKK4yeast, homolog of
- MEKK 4
- mitogen-activated protein kinase kinase kinase 4
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