MEKK3 Antibody

Images

 
Western Blot: MEKK3 Antibody [H00004215-D03P] - Analysis of MAP3K3 expression in HeLa.
Proximity Ligation Assay: MEKK3 Antibody [H00004215-D03P] - Analysis of protein-protein interactions between MAP3K3 and MAP2K5. HeLa cells were stained with anti-MAP3K3 rabbit purified polyclonal 1:1200 and anti-MAP2K5 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PLA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MEKK3 Antibody Summary

Immunogen
MAP3K3 (AAH10464.1, 1 a.a. - 90 a.a.) full-length human protein. MNEANVMLPYSGKEEPVLPVAMTLPLPGRGPRCGTAATEGGSSFVNAVVSVLQVGVTLMLYPVSKLETVCALWALSTPALGLGLGCIEKS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAP3K3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Proximity Ligation Assay
Application Notes
It has been used for WB.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MEKK3 Antibody

  • EC 2.7.11.25
  • MAP/ERK kinase kinase 3
  • MAP3K3
  • MAPK/ERK kinase kinase 3
  • MAPKKK3
  • MAPKKK3MEKK 3
  • MEK kinase 3
  • MEKK3
  • mitogen-activated protein kinase kinase kinase 3

Background

MEKK3 is a Ser/Thr protein kinase belonging to the MAP/ERK kinase kinase family (1). Closely related to MEKK2, MEKK3 is expressed in a multitude of tissues. MEKK3 directly regulates SAPKs and ERKs pathway via SEK and MEK1, respectively but not the p38 pathway (2) and is also involved in the NF-kB pathway (3). MEKK3 as well as MEKK2 bind, phosphorylate and activate MEK5 through their PB1 domain (4). hKSR-2 (human kinase suppressor of ras-2) has been shown to regulate the activity of MEKK3 (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-24756
Species: Hu
Applications: WB, IHC-P
NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
MAB17761
Species: Hu, Mu, Rt
Applications: WB, ICC
NBP1-89655
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
AF2848
Species: Hu, Mu
Applications: WB, ICC
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NB500-138
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-44405
Species: Hu
Applications: Flow, IHC-P, IF
AF467
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
NBP2-37568
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC
NBP2-00764
Species: Hu
Applications: WB, Flow, IHC, IHC-P
NBP1-81575
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-68874
Species: Hu, Mu, Rt
Applications: WB, PEP-ELISA
NBP1-88419
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
25910002
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, IP
NB100-56363
Species: Hu, Mu
Applications: WB
H00004215-D03P
Species: Hu
Applications: WB, PLA

Publications for MEKK3 Antibody (H00004215-D03P) (0)

There are no publications for MEKK3 Antibody (H00004215-D03P).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for MEKK3 Antibody (H00004215-D03P) (0)

There are no reviews for MEKK3 Antibody (H00004215-D03P). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for MEKK3 Antibody (H00004215-D03P) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional MEKK3 Products

Bioinformatics Tool for MEKK3 Antibody (H00004215-D03P)

Discover related pathways, diseases and genes to MEKK3 Antibody (H00004215-D03P). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for MEKK3 Antibody (H00004215-D03P)

Discover more about diseases related to MEKK3 Antibody (H00004215-D03P).
 

Pathways for MEKK3 Antibody (H00004215-D03P)

View related products by pathway.

PTMs for MEKK3 Antibody (H00004215-D03P)

Learn more about PTMs related to MEKK3 Antibody (H00004215-D03P).
 

Research Areas for MEKK3 Antibody (H00004215-D03P)

Find related products by research area.

Blogs on MEKK3

There are no specific blogs for MEKK3, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our MEKK3 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol MAP3K3
Entrez