MEKK3 Products

Antibodies
MEKK3 Antibody (576240)
MEKK3 Antibody (576240)
MAB6095
Species: Hu
Applications: WB
Host: Mouse Monoclonal
MEKK3 Antibody
MEKK3 Antibody
NBP2-17273
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
MEKK3 Antibody
MEKK3 Antibody
NBP2-58303
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
MEKK3 Overexpression Lysate ( ...
MEKK3 Overexpression Lysate (Denat...
H00004215-T01
Species: Hu
Applications: WB
MEKK3 Overexpression Lysate ( ...
MEKK3 Overexpression Lysate (Native)
NBL1-12855
Applications: WB
Proteins
Recombinant Human MEKK3 Prote ...
Recombinant Human MEKK3 Protein
H00004215-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human MEKK3 Prote ...
Recombinant Human MEKK3 Protein
H00004215-P01
Species: Hu
Applications: WB, ELISA, PA
MEKK3 Recombinant Protein Ant ...
MEKK3 Recombinant Protein Antigen
NBP2-34004PEP
Species: Hu
Applications: AC
RNAi
MEKK3 RNAi
MEKK3 RNAi
H00004215-R06
Species: Hu
Applications: RNAi, RNAi SP
MEKK3 RNAi
MEKK3 RNAi
H00004215-R05
Species: Hu
Applications: RNAi, RNAi SP

Description

MEKK3 is a Ser/Thr protein kinase belonging to the MAP/ERK kinase kinase family (1). Closely related to MEKK2, MEKK3 is expressed in a multitude of tissues. MEKK3 directly regulates SAPKs and ERKs pathway via SEK and MEK1, respectively but not the p38 pathway (2) and is also involved in the NF-kB pathway (3). MEKK3 as well as MEKK2 bind, phosphorylate and activate MEK5 through their PB1 domain (4). hKSR-2 (human kinase suppressor of ras-2) has been shown to regulate the activity of MEKK3 (5).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 4215
Alternate Names
  • EC 2.7.11.25
  • MAPK/ERK kinase kinase 3
  • MAP/ERK kinase kinase 3
  • MEKK3
  • MAPKKK3MEKK 3
  • MEK kinase 3
  • mitogen-activated protein kinase kinase kinase 3

Research Areas for MEKK3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Immunology
Innate Immunity
Protein Kinase

PTMs for MEKK3

Learn more about PTMs related to MEKK3.

Phosphorylation
Ubiquitination
Cleavage
Methylation
Dephosphorylation

Bioinformatics Tool for MEKK3

Discover related pathways, diseases and genes to MEKK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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