MEK2 Antibody (300317) [Alexa Fluor® 405]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF
• Clone: 300317
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

MEK2 Antibody (300317) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human MEK2
  Met1-Val400
  Accession # P36507
• Specificity: Detects human, mouse, and rat MEK2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) MEK1 or rhMEK5 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MEK2 Antibody (300317) [Alexa Fluor® 405]

• ERK activator kinase 2
• MAP2K2
• MAPKK 2
• MEK 2
• MEK2
• MEK2EC 2.7.12.2
• mitogen-activated protein kinase kinase 2
• MKK2
• MKK2FLJ26075
• p45
• PRKMK2MAPKK2

Background

Mitogen-activated protein kinase kinase 2 (MEK2 or MAP2K2), also known as MKK2,belongs to the STE family of kinases. Both MEK2 and the related MEK1 aredual‑specificity kinases, phosphorylating and activating the mitogen-activated proteinkinases ERK1 and ERK2 at T and Y positions within the phosphoacceptor sequence T-E-Y. Activation of MEK2 by Raf occurs through phosphorylation at S222 and S226.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.