Species: Hu, Ca, Mk
Applications: WB, IHC, IF
Host: Mouse monoclonal
Applications: WB, Flow, IHC, IHC-P
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ca
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
WB, ELISA, PA
Applications: RNAi, RNAi SP
MEK1 and MEK2 (MAPK kinase 1/2, or ERK kinase 1/2) are mitogen-activated protein kinases that stimulate MAP kinase activity, playing a role in both cell growth and differentiation (1,2). MEK itself is activated via phosphorylation at serines 217/218 and 221/222 by upstream activator kinases, including c-raf, mos and MEK kinase (3,4). MEK1 and MEK2 are activated by a wide variety of growth factors and cytokines, and also by membrane depolarization and calcium influx (5).
Bioinformatics Tool for MEK2
Discover related pathways, diseases and genes to MEK2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.