MEK2 Antibody (1721) [Alexa Fluor® 700]

Product Discontinued

MEK2 Antibody (1721) [Alexa Fluor® 700] Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human MEK2. The exact sequence is proprietary.
• Predicted Species: Mouse (91%), Rat (92%), Porcine (93%), Bovine (93%), Chicken (91%), Canine (93%). Backed by our 100% Guarantee.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAP2K2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for MEK2 Antibody (1721) [Alexa Fluor® 700]

• ERK activator kinase 2
• MAP2K2
• MAPKK 2
• MEK 2
• MEK2
• MEK2EC 2.7.12.2
• mitogen-activated protein kinase kinase 2
• MKK2
• MKK2FLJ26075
• p45
• PRKMK2MAPKK2

Background

MEK1 and MEK2 (MAPK kinase 1/2, or ERK kinase 1/2) are mitogen-activated protein kinases that stimulate MAP kinase activity, playing a role in both cell growth and differentiation (1,2). MEK itself is activated via phosphorylation at serines 217/218 and 221/222 by upstream activator kinases, including c-raf, mos and MEK kinase (3,4). MEK1 and MEK2 are activated by a wide variety of growth factors and cytokines, and also by membrane depolarization and calcium influx (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAP2K2