MED13 Products

Description

MED13 encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.

Bioinformatics

Entrez	9969 Human
Uniprot	Q9UHV7 Human NP_005112.2 Human
Product By Gene ID	9969
Alternate Names	Vitamin D3 receptor-interacting protein complex component DRIP250 Trap240 Thyroid hormone receptor-associated protein complex 240 kDa component thyroid hormone receptor-associated protein, 240 kDa subunit Thyroid hormone receptor-associated protein 1 thyroid hormone receptor-associated protein complex component TRAP240 Activator-recruited cofactor 250 kDa component mediator of RNA polymerase II transcription, subunit 13 homolog thyroid hormone receptor associated protein 1 THRAP1mediator of RNA polymerase II transcription subunit 13 KIAA0593HSPC221 TRAP240DRIP250 mediator complex subunit 13ARC250

Diseases related to MED13

Discover more about diseases related to MED13.

Hypoxia
Heart Failure
Physiological Stress
Heart Diseases
Obesity
Adolescent Idiopathic Scoliosis
Insulin Resistance
Dysplasia
Congenital Heart Defects
Fibrosis
Metabolic Syndrome X
Congenital Heart Disease
Body Dysmorphic Disorders
Malignant Neoplasms
Neoplasms
Scoliosis, Unspecified
Dwarfism

Pathways for MED13

View related products by pathway and learn more about each of the pathways below.

Rna Interference
Energy Homeostasis
Cell Division
Transport
Response To Stress
Cell Development
Nodal Signaling Pathway
Response To Hypoxia
Fertilization
Biofilm Formation
Auxin Transport
Crystal Cell Differentiation
Virulence
Localization
Embryo Development
Asymmetric Cell Division
Mrna Transcription
Cell Differentiation
Pathogenesis
Oncogenesis

PTMs for MED13

Learn more about PTMs related to MED13.

Phosphorylation
Cleavage

Bioinformatics Tool for MED13

Discover related pathways, diseases and genes to MED13. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.