MDC1 Antibody (398636) [PerCP]

• Reactivity: Hu
• Applications: WB
• Clone: 398636
• Clonality: Monoclonal
• Host: Rat
• Conjugate: PerCP

MDC1 Antibody (398636) [PerCP] Summary

• Immunogen:

  E.coli-derived recombinant human MDC1

  
  Met1-Glu335
  Accession # Q14676
• Specificity: Detects human MDC1 in Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: MDC1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for MDC1 Antibody (398636) [PerCP]

• DKFZp781A0122
• Em:AB023051.5
• KIAA0170MGC166888
• MDC1
• mediator of DNA damage checkpoint 1
• mediator of DNA damage checkpoint protein 1
• mediator of DNA-damage checkpoint 1
• NFBD1
• NFBD1homologue to Drosophila photoreceptor protein calphotin
• Nuclear factor with BRCT domains 1

Background

MDC1 works with H2AX to promote recruitment of repair proteins to the sites of DNA breaks and controls damage-induced cell-cycle arrest checkpoints. Cells that lack MDC1 are sensitive to ionizing radiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MDC1