MAML1 Antibody (2E710.1)

Product Discontinued

MAML1 Antibody (2E710.1) Summary

• Immunogen: Normal jejunal epithelial brush border-enriched membranes from a non-secretor, blood group O
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAML1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
• Application Notes: EIA

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for MAML1 Antibody (2E710.1)

• FLJ53540
• KIAA0200Mam1
• Mam-1mastermind homolog
• mastermind (drosophila)-like 1
• mastermind-like 1 (Drosophila)
• mastermind-like protein 1

Background

MAML1 is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAML1