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MAdCAM-1 Antibody [DyLight 650] - (Research Grade ontamalimab Biosimilar)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clonality
Monoclonal
Host
Human
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28052AF350
Alexa Fluor 405
NBP3-28052AF405
Alexa Fluor 488
NBP3-28052AF488
Alexa Fluor 532
NBP3-28052AF532
Alexa Fluor 594
NBP3-28052AF594
Alexa Fluor 647
NBP3-28052AF647
Alexa Fluor 700
NBP3-28052AF700
Alexa Fluor 750
NBP3-28052AF750
Allophycocyanin
NBP3-28052APC
Biotin
NBP3-28052B
CoraFluor 1
NBP3-28052CL1
DyLight 350
NBP3-28052UV
DyLight 405
NBP3-28052V
DyLight 488
NBP3-28052G
DyLight 550
NBP3-28052R
DyLight 594
NBP3-28052DL594
DyLight 680
NBP3-28052FR
DyLight 755
NBP3-28052IR
FITC
NBP3-28052F
HRP
NBP3-28052H
Janelia Fluor 525
NBP3-28052JF525
Janelia Fluor 549
NBP3-28052JF549
Janelia Fluor 646
NBP3-28052JF646
Janelia Fluor 669
NBP3-28052JF669
PE
NBP3-28052PE
PerCP
NBP3-28052PCP
Unconjugated
NBP3-28052-100ug
mFluor Violet 450 SE
NBP3-28052MFV450
mFluor Violet 500 SE
NBP3-28052MFV500
mFluor Violet 610 SE
NBP3-28052MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-28052-100ug
Low Endotoxin, Azide and BSA Free
NBP3-28052-100ug
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MAdCAM-1 Antibody [DyLight 650] - (Research Grade ontamalimab Biosimilar) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
MADCAM1
Isotype
IgG2
Clonality
Monoclonal
Host
Human
Gene
MADCAM1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MAdCAM-1 Antibody [DyLight 650] - (Research Grade ontamalimab Biosimilar)

  • hMAdCAM-1
  • MACAM1
  • MAdCAM1
  • MAdCAM-1
  • mucosal addressin cell adhesion molecule 1
  • mucosal addressin cell adhesion molecule-1
  • mucosal vascular addressin cell adhesion molecule 1

Background

Mucosal vascular addressin-1 (MAdCAM-1) is a type I transmembrane glycoprotein expressed at high levels on high endothelial venules (HEV) of Peyer's patches and mesenteric lymph nodes, and on flat walled venules within the gut lamina propria. It is also expressed on sinus-lining cells in the spleen. (1-3) The countereceptor or "homing receptor" for MAdCAM-1 is alpha4beta7 integrin (also known as LPAM-1). MAdCAM-1 is also a facultative ligand for CD62L/L-selectin. (4, 5) The monoclonal antibody MECA-367 binds to the first domain of MAdCAM-1 and blocks MAdCAM-1-dependent binding in vitro and lymphocyte homing to Peyer's patch HEV in vivo. (1, 2, 4)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MADCAM1