MAdCAM-1 Products

Antibodies
MAdCAM-1 Antibody [Unconjugat ...
MAdCAM-1 Antibody [Unconjugated]
AF993
Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
MAdCAM-1 Antibody (MECA-367)
MAdCAM-1 Antibody (MECA-367)
NBP1-28146
Species: Mu
Applications: WB, B/N, Flow, IHC, IHC-Fr, IP
Host: Rat Monoclonal
MAdCAM-1 Antibody (200530)
MAdCAM-1 Antibody (200530)
MAB9931
Species: Mu
Applications: ELISA(Cap)
Host: Rat Monoclonal
Lysates
MAdCAM-1 Overexpression Lysat ...
MAdCAM-1 Overexpression Lysate (Na...
NBP2-05730
Applications: WB
MAdCAM-1 Overexpression Lysat ...
MAdCAM-1 Overexpression Lysate (Na...
NBP2-05729
Applications: WB

Description

Mucosal vascular addressin-1 (MAdCAM-1) is a type I transmembrane glycoprotein expressed at high levels on high endothelial venules (HEV) of Peyer's patches and mesenteric lymph nodes, and on flat walled venules within the gut lamina propria. It is also expressed on sinus-lining cells in the spleen. (1-3) The countereceptor or "homing receptor" for MAdCAM-1 is alpha4beta7 integrin (also known as LPAM-1). MAdCAM-1 is also a facultative ligand for CD62L/L-selectin. (4, 5) The monoclonal antibody MECA-367 binds to the first domain of MAdCAM-1 and blocks MAdCAM-1-dependent binding in vitro and lymphocyte homing to Peyer's patch HEV in vivo. (1, 2, 4)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Mouse
Product By Gene ID 8174
Alternate Names
  • MACAM1
  • MAdCAM-1
  • mucosal addressin cell adhesion molecule 1
  • hMAdCAM-1
  • mucosal addressin cell adhesion molecule-1
  • mucosal vascular addressin cell adhesion molecule 1

PTMs for MAdCAM-1

Learn more about PTMs related to MAdCAM-1.

Phosphorylation
Carboxylation
Biotinylation
Deamination
Acylation

Bioinformatics Tool for MAdCAM-1

Discover related pathways, diseases and genes to MAdCAM-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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