LRRN2 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

LRRN2 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human LRRN2.
  
  

  Source: E. coli

  Amino Acid Sequence: GADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTK

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: LRRN2
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-84686.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 30 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for LRRN2 Recombinant Protein Antigen

• FIGLER7
• GAC1
• GAC1LRRN5
• Glioma amplified on chromosome 1 protein
• immunoglobulin and leucine rich repeat domain 7
• leucine rich and ankyrin repeats 1
• leucine rich repeat neuronal 2
• leucine rich repeat neuronal 5
• leucine-rich repeat neuronal protein 2
• Leucine-rich repeat neuronal protein 5
• LRANK1
• LRRN2
• LRRN5

Background

LRRN2, also known as Leucine-rich repeat neuronal protein 2, is a 78.9 kDa, 713 amino acid protein that is involved in signal transduction reception and cell adhesion as a member of the leucine-rich repeat superfamily. Current research is studying the effects of the protein on diseases and disorders such as neuronitis and malignant glioma. The protein interacts in signal transduction pathways with other proteins including NEUROD4 and VCL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LRRN2