LPAR2/LPA2/EDG-4 Antibody

Immunohistochemistry-Paraffin: LPAR2/LPA2/EDG-4 Antibody [NLS3759] - Analysis of anti-LPAR2 antibody with human brain, cortex.

Immunohistochemistry-Paraffin: LPAR2/LPA2/EDG-4 Antibody [NLS3759] - Analysis of anti-LPAR2 antibody with pancreas, carcinoma.

Immunohistochemistry-Paraffin: LPAR2/LPA2/EDG-4 Antibody [NLS3759] - Analysis of anti-LPAR2 antibody with transfection control.

Immunohistochemistry-Paraffin: LPAR2/LPA2/EDG-4 Antibody [NLS3759] - Analysis of anti-LPAR2 antibody with transfection positive.

Product Discontinued

LPAR2/LPA2/EDG-4 Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human LPAR2 / EDG4.
• Localization: Plasma membrane
• Specificity: Human LPAR2 / EDG4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (94%), Porcine (100%), Bovine (100%), Monkey (100%), Primate (100%), Equine (100%), Canine (100%), Bat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LPAR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 - 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Panda (100%), Elephant (94%), Rat (89%), Rabbit (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for LPAR2/LPA2/EDG-4 Antibody

• EDG4
• EDG-4
• EDG4FLJ93869
• endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor4,LPA receptor EDG4
• G protein-coupled receptor
• LPA2
• LPA-2
• LPA2LPA receptor 2
• LPAR2
• lysophosphatidic acid receptor 2
• lysophosphatidic acid receptor EDG4
• Lysophosphatidic acid receptor Edg-4

Background

Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LPAR2
• Entrez:
  • 9170(Human)