LOK Antibody

ELISA: LOK Antibody [30900002] - Affinity Purified

Product Discontinued

LOK Antibody Summary

• Immunogen: This antibody is specific for the Middle Region of the target protein.
• Specificity: This product is specific for Human STK10.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STK10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: This antibody is useful in ELISA.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for LOK Antibody

• EC 2.7.11
• EC 2.7.11.1
• LOKserine/threonine-protein kinase 10
• Lymphocyte-oriented kinase
• PRO2729
• serine/threonine kinase 10

Background

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LOK Antibody (30900002)(2)

Publications using 30900002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

FAQs for LOK Antibody (30900002). (Showing 1 - 1 of 1 FAQs).

1. Could you please provide more acute data than middle region for the immunogen of cat# 30900002 ? Could you provide peptide sequence or the aa range? I don't understand because middle region doesn't mean c-terminal ?!!
   • The full sequence for this request is: mafanfrril rlstfekrks reyehvrrdl dpnevweivg elgdgafgkv ykaknketga laaakvietk seeeledyiv eieilatcdh pyivkllgay yhdgklwimi efcpggavda imleldrglt epqiqvvcrq mlealnflhs kriihrdlka gnvlmtlegd irladfgvsa knlktlqkrd sfigtpywma pevvmcetmk dtpydykadi wslgitliem aqiepphhel npmrvllkia ksdpptlltp skwsvefrdf lkialdknpe trpsaaqlle hpfvssitsn kalrelvaea kaevmeeied grdegeeeda vdaastlenh tqnssevspp slnadkplee spstplapsq sqdsvnepcs qpsgdrslqt tsppvvapgn englavpvpl rksrpvsmda riqvaqekqv aeqggdlspa anrsqkasqs rpnssaletl ggeklangsl eppaqaapgp skrdsdcssl ctsesmdygt nlstdlslnk emgslsikdp klykktlkrt rkfvvdgvev sittskiise dekkdeemrf lrrqelrelr llqkeehrnq tqlsnkhelq leqmhkrfeq einakkkffd telenlerqq kqqvekmeqd havrrreear rirleqdrdy trfqeqlklm kkevknevek lprqqrkesm kqkmeehtqk kqlldrdfva kqkedlelam krlttdnrre icdkereclm kkqellrdre aalwemeehq lqerhqlvkq qlkdqyflqr hellrkheke reqmqrynqr mieqlkvrqq qekarlpkiq rsegktrmam ykkslhingg gsaaeqreki kqfsqqeekr qkserlqqqq khenqmrdml aqcesnmsel qqlqnekchl lvehetqklk aldeshnqnl kewrdklrpr kkaleedlnq kkreqemffk lseeaecpnp stpskaakff pyssadas The best I can tell you is the a.a. sequence is towards the C terminal. It is in the middle region towards the C terminal, not the N terminal. I hope that clarifies!

Bioinformatics

• Gene Symbol: STK10
• Uniprot:
  • O94804(Human)