Species: Hu
Applications: WB, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
LOK encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and over expression of a kinase dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase 1 pathway.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human |
| Product By Gene ID |
6793 |
| Alternate Names |
- EC 2.7.11
- EC 2.7.11.1
- LOKserine/threonine-protein kinase 10
- Lymphocyte-oriented kinase
- PRO2729
- serine/threonine kinase 10
|
Research Areas for LOK
Find related products by research area and learn more about each of the different research areas below.
Protein Kinase