LH beta Antibody (L1) - BSA Free

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: L1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

LH beta Antibody (L1) - BSA Free Summary

• Description: Novus Biologicals Mouse LH beta Antibody (L1) - BSA Free (NB100-73010) is a monoclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified natural LH beta.
• Specificity: High affinity for the beta chain of LH. No cross-reaction with FSH, TSH or HCG.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LHB
• Purity: Ion exchange chromatography

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: Recommended pair for sandwich immunoassay (capture - detection): NB100-73010 - NB100-73003.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM Tris (pH 7.5) and 0.15M NaCl
• Preservative: 0.05% Sodium Azide
• Purity: Ion exchange chromatography

Alternate Names for LH beta Antibody (L1) - BSA Free

• CGB4
• hLHB
• interstitial cell stimulating hormone, beta chain
• LH beta
• LHB
• LSH-B
• LSH-beta
• luteinizing hormone beta polypeptide
• luteinizing hormone beta subunit
• lutropin beta chain
• Lutropin beta
• lutropin subunit beta

Background

LH is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for LH beta Antibody (NB100-73010). (Showing 1 - 1 of 1 FAQ).

1. Is there any cross-reactivity with LH-alpha?
   • Our LH beta antibody with catalogue number NB100-73010 was raised against purified human LH beta, for which it has a high affinity. It has been shown not to cross-react with FSH, TSH or HCG, however we unfortunately have no testing data where we have used the antibody against LH alpha. An alignment of the human LHB and LHA sequences shows little homology, and so cross-reactivity seems unlikely, however we have not confirmed this in our lab.

Bioinformatics

• Gene Symbol: LHB
• Entrez:
  • 3972(Human)