LH beta Antibody (L1) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: L1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

LH beta Antibody (L1) [Janelia Fluor® 669] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified natural LH beta.
• Specificity: High affinity for the beta chain of LH. No cross-reaction with FSH, TSH or HCG.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LHB
• Purity: Ion exchange chromatography

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-73010. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Ion exchange chromatography

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for LH beta Antibody (L1) [Janelia Fluor® 669]

• CGB4
• hLHB
• interstitial cell stimulating hormone, beta chain
• LH beta
• LHB
• LSH-B
• LSH-beta
• luteinizing hormone beta polypeptide
• luteinizing hormone beta subunit
• lutropin beta chain
• Lutropin beta
• lutropin subunit beta

Background

LH is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LHB