LAX1 Antibody

Western Blot: LAX1 Antibody [NBP1-83662] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11Lane 2: Human cell line RT-4Lane 3: Human cell line U-251MG sp

Immunocytochemistry/Immunofluorescence: LAX1 Antibody [NBP1-83662] - Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & the Golgi apparatus.

Immunohistochemistry-Paraffin: LAX1 Antibody [NBP1-83662] - Staining of human liver.

Immunohistochemistry-Paraffin: LAX1 Antibody [NBP1-83662] - Staining of human tonsil shows cytoplasmic positivity in lymphoid cells outside reaction centra.

Immunohistochemistry-Paraffin: LAX1 Antibody [NBP1-83662] - Staining of human cerebral cortex, kidney, liver and tonsil using Anti-LAX1 antibody NBP1-83662 (A) shows similar protein distribution across tissues to independent antibody NBP1-83661 (B).

Immunohistochemistry-Paraffin: LAX1 Antibody [NBP1-83662] - Staining of human kidney.

Immunohistochemistry-Paraffin: LAX1 Antibody [NBP1-83662] - Staining of human cerebral cortex.

Immunohistochemistry-Paraffin: LAX1 Antibody [NBP1-83662] - Staining of human tonsil.

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

LAX1 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: AEDSDSLSNGEGSSQISNDYVNMTGLDLSAIQERQLWVAFQCCRDYENVPAADPSGSQQQAEKDVPSSNIGHVEDKTDDPGTHVQCVKRTFLASGDYADFQPFTQSEDSQMKHREEMSNEDSSDYENVLTAKLGGRDSEQGP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LAX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  LAX1 Protein (NBP1-83662PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for LAX1 Antibody

• LAT-like membrane associated protein
• LAX1
• LAXFLJ20340
• Linker for activation of X cells
• lymphocyte transmembrane adapter 1
• lymphocyte transmembrane adaptor 1
• Membrane-associated adapter protein LAX

Background

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LAX1