Latent TGF-beta bp1 Antibody

Product Discontinued

Latent TGF-beta bp1 Antibody Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: LTBP1 (NP_000618 403 a.a. - 500 a.a.) partial recombinant protein with GST tag. CPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLS
• Specificity: LTBP1 - latent transforming growth factor beta binding protein 1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: LTBP1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Latent TGF-beta bp1 Antibody

• Latent TGFbeta bp1
• Latent TGF-beta bp1
• latent transforming growth factor beta binding protein 1
• latent-transforming growth factor beta-binding protein 1
• LTBP1
• LTBP-1
• MGC163161
• TGF-beta1-BP-1
• Transforming growth factor beta-1-binding protein 1

Background

The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Latent TGF-beta bp1 Antibody (H00004052-A01)(1)

Publication using H00004052-A01

• Kang UB, Yeom J, Kim HJ et al. Expression profiling of more than 3500 proteins of MSS-type colorectal cancer by stable isotope labeling and mass spectrometry. J Proteomics. 2011-12-26 [PMID: 22154799]

Bioinformatics

• Gene Symbol: LTBP1
• Entrez:
  • 4052(Human)
• OMIM:
  • 150390(Human)
• Uniprot:
  • NP_000618(Human)