LAR/PTPRF Antibody

Western Blot: LAR/PTPRF Antibody [H00005792-B01P] - Analysis of PTPRF expression in transfected 293T cell line by PTPRF polyclonal antibody. Lane 1: PTPRF transfected lysate(38.83 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

LAR/PTPRF Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: PTPRF (ENSP00000361488, 1 a.a. - 353 a.a.) full-length human protein. MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSPWCRHARDCHGPSLFSFLLLSAAAATAPTGQVPGVCHYFAFLPCRPMGKQPLLGAFVSFVGLAAWARSPMGIWSHPIRLLGVCACVCAHTGTLICV
• Specificity: Reacts with protein tyrosine phosphatase, receptor type, F.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: PTPRF
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LAR/PTPRF Antibody

• LAR
• LCA-homolog
• protein tyrosine phosphatase, receptor type, F
• PTPRF
• receptor type, F polypeptide
• receptor-linked protein-tyrosine phosphatase LAR
• receptor-type tyrosine-protein phosphatase F

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRF
• Entrez:
  • 5792(Human)
• Uniprot:
  • ENSP00000361488(Human)