LAR/PTPRF Antibody

Images

 
Western Blot: LAR/PTPRF Antibody [H00005792-B01P] - Analysis of PTPRF expression in transfected 293T cell line by PTPRF polyclonal antibody. Lane 1: PTPRF transfected lysate(38.83 KDa). Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

LAR/PTPRF Antibody Summary

Immunogen
PTPRF (ENSP00000361488, 1 a.a. - 353 a.a.) full-length human protein. MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSPWCRHARDCHGPSLFSFLLLSAAAATAPTGQVPGVCHYFAFLPCRPMGKQPLLGAFVSFVGLAAWARSPMGIWSHPIRLLGVCACVCAHTGTLICV
Specificity
Reacts with protein tyrosine phosphatase, receptor type, F.
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
PTPRF
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LAR/PTPRF Antibody

  • LAR
  • LCA-homolog
  • protein tyrosine phosphatase, receptor type, F
  • PTPRF
  • receptor type, F polypeptide
  • receptor-linked protein-tyrosine phosphatase LAR
  • receptor-type tyrosine-protein phosphatase F

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PTPRF
Entrez
Uniprot