Laminin alpha 2 Antibody (1003531) [DyLight 594]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 1003531
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 594

Laminin alpha 2 Antibody (1003531) [DyLight 594] Summary

• Immunogen: Chinese Hamster Ovary cell line, CHO-derived human Laminin alpha 2
  Lys2145-Asn3122
  Accession # P24043
• Specificity: Detects human Laminin alpha 2 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Laminin alpha 2 Antibody (1003531) [DyLight 594]

• LAMA2
• Laminin alpha 2
• Laminin M chain
• laminin subunit alpha-2
• laminin, alpha 2
• Laminin-12 subunit alpha
• Laminin-2 subunit alpha
• LAMM
• LAMMLaminin-4 subunit alpha
• Merosin heavy chain
• Merosin

Background

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.