Laminin alpha 2 Products

Description

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Bioinformatics

Entrez	3908 Human
Uniprot	NP_000417 Human
Product By Gene ID	3908
Alternate Names	LAMA2 Laminin alpha 2 Laminin M chain laminin subunit alpha-2 laminin, alpha 2 Laminin-12 subunit alpha Laminin-2 subunit alpha LAMM LAMMLaminin-4 subunit alpha Merosin heavy chain Merosin