Recombinant Mouse LAIR1 Protein

Product Discontinued

Recombinant Mouse LAIR1 Protein Summary

• Description: A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids22-144 of Mouse LAIR1
  
  

  Source:Baculovirus

  Amino Acid Sequence: ADPQEGSLPD ITIFPNSSLM ISQGTFVTVV CSYSDKHDLY NMVRLEKDGS TFMEKSTEPY KTEDEFEIGP VNETITGHYS CIYSKGITWS ERSKTLELKV IKENVIQTPA PGPTSDTSWL KTYSIYHHHH HH

• Source: Baculovirus
• Protein/Peptide Type: Recombinant Protein
• Gene: LAIR1
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 15 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% glycerol
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Mouse LAIR1 Protein

• CD305 antigen
• CD305
• CD305leukocyte-associated Ig-like receptor 1
• HLAIR1
• LAIR1
• LAIR-1
• leukocyte-associated immunoglobulin-like receptor 1

Background

Lair1, as known as leukocyte-associated immunoglobulin-like receptor 1 isoform a, is an inhibitory receptor of the lg superfamily that is related to inhibitory members of KIR and ILT/CD85 families. This protein is well expressed NK cells, T cells, B cells, monocytes, macrophages, immature neutrophils, dendritic cells and most thymocytes. Also, it functions as an inhibitory receptor not only on NK cells, but on human T cells. Recombinant mouse Lair1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: LAIR1
• Uniprot:
  • NP_001106945()