23.2 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20 mM Tris-HCl buffer (pH8.0), 0.1 M NaCl, 1 mM DTT, 10% glycerol
>90%, by SDS-PAGE
Alternate Names for Recombinant Human KRAS His Protein
cellular c-Ki-ras2 proto-oncogene
Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog
K-ras p21 protein
PR310 c-K-ras oncogene
transforming protein p21
v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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