KPNA3 Antibody

Images

 
Western Blot: KPNA3 Antibody [NBP1-52976] - Human Fetal Lung, Antibody Dilution: 1.0 ug/ml.
Western Blot: KPNA3 Antibody [NBP1-52976] - HepG2.
Western Blot: KPNA3 Antibody [NBP1-52976] - Hela.
Western Blot: KPNA3 Antibody [NBP1-52976] - Human Fetal Lung.
Western Blot: KPNA3 Antibody [NBP1-52976] - MCF-7 whole cell lysates, concentration 0.2-1 ug/ml.
Tissue Culture Substratum: KPNA3 Antibody [NBP1-52976] - Human Fetal Brain.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, TCS
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

KPNA3 Antibody Summary

Immunogen
Synthetic peptides corresponding to KPNA3(karyopherin alpha 3 (importin alpha 4)) The peptide sequence was selected from the N terminal of KPNA3. Peptide sequence AENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV.
Specificity
This product is specific to Subunit or Isofrom: alpha-3.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KPNA3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Tissue Culture Substratum
Application Notes
This is a rabbit polyclonal antibody against KPNA3 and was validated on Western blot.
Theoretical MW
58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with sterilized PBS to a final concentration of 1mg/ml. Vortex followed by Centrifuge again to pellet the solution.

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for KPNA3 Antibody

  • hSRP1
  • importin alpha 4
  • Importin alpha Q2
  • importin alpha-3
  • importin subunit alpha-3
  • importin-alpha-Q2
  • IPOA4
  • karyopherin alpha 3 (importin alpha 4)
  • Karyopherin subunit alpha-3
  • qip2
  • SRP1
  • SRP1gamma
  • SRP1-gamma
  • SRP4

Background

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KPNA3 Antibody (NBP1-52976) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KPNA3
Uniprot