klra3 Antibody - BSA Free

Western Blot: klra3 Antibody [NBP1-76335] - Mouse brain tissue lysate with KLRA3 antibody at 2 ug/ml.

• Reactivity: Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

klra3 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA3. The immunogen is located within the last 50 amino acids of KLRA3.
• Specificity: This antibody may cross-react with other LY49 receptors.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLRA3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 2 ug/ml
• Theoretical MW: 31 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  klra3 Peptide (NBP1-76335PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for klra3 Antibody - BSA Free

• 5E6
• Klra3 killer cell lectin-like receptor, subfamily A, member 3
• Ly49c
• Nk2
• Nk-2
• Nk2.1
• NK-2.1

Background

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb. This antibody may cross-react with other LY49 receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLRA3
• Uniprot:
  • Q3ZB40(Mouse)