KLRA1 Antibody - BSA Free

Western Blot: KLRA1 Antibody [NBP1-76983] - 293 cell lysate with KLRA1 antibody at (A) 1 ug/ml and (B) 2 ug/ml.

Immunohistochemistry: KLRA1 Antibody - BSA Free [NBP1-76983] - Immunohistochemistry of KLRA1 in human spleen tissue with KLRA1 antibody at 2.5 ug/mL.

Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-76983] - Immunofluorescence of KLRA1 in Human Spleen cells with KLRA1 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

KLRA1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit KLRA1 Antibody - BSA Free (NBP1-76983) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human KLRA1. The immunogen is located within amino acids 190 - 240 of KLRA1. Amino Acid Squence: IGLSYDERESKWK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLRA1P
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  KLRA1 Peptide (NBP1-76983PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for KLRA1 Antibody - BSA Free

• killer cell lectin-like receptor subfamily A pseudogene 1
• KLRA#
• KLRA1
• Ly49
• LY49L
• Ly-49L
• MGC126520
• MGC126522

Background

KLRA1 (also known and Ly49L) is a member of the LY49 family of receptors Natural killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLRA1P
• Uniprot:
  • EAW96194(Human)