KLF11 Antibody (8F4) - Azide and BSA Free

Western Blot: KLF11 Antibody (8F4) [H00008462-M01] - KLF11 monoclonal antibody (M01), clone 8F4 Analysis of KLF11 expression in Hela S3 NE.

Immunocytochemistry/Immunofluorescence: KLF11 Antibody (8F4) [H00008462-M01] - Analysis of monoclonal antibody to KLF11 on HeLa cell. Antibody concentration 10 ug/ml.

Immunohistochemistry-Paraffin: KLF11 Antibody (8F4) [H00008462-M01] - Analysis of monoclonal antibody to KLF11 on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration 3 ug/ml.

ELISA: KLF11 Antibody (8F4) [H00008462-M01] - Detection limit for recombinant GST tagged KLF11 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 8F4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

KLF11 Antibody (8F4) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: KLF11 (NP_003588, 404 a.a. ~ 512 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
• Specificity: KLF11 - Kruppel-like factor 11
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: KLF11
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF, IHC-P and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for KLF11 Antibody (8F4) - Azide and BSA Free

• FKLFFKLF1
• Krueppel-like factor 11
• Kruppel-like factor 11
• MODY7TGFB-inducible early growth response protein 2
• TIEG-2
• TIEG2TGFB inducible early growth response 2
• Tieg3
• Transforming growth factor-beta-inducible early growth response protein 2

Background

Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KLF11 Antibody (H00008462-M01)(5)

Publications using H00008462-M01

• Wenying L, Haocheng L, Jinjian S et al. KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression. Thromb Haemost. 2021-08-24 [PMID: 34428834]
• Qiao C, Li S, Lu H et al. Laminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells. Sci Rep 2018-02-05 [PMID: 29403061]
• Zheng Y, Khan Z, Zanfagnin V et al. Epigenetic Modulation of Collagen 1A1: Therapeutic Implications in Fibrosis and Endometriosis. Biol Reprod 2016-04-01 [PMID: 26935598]
• Zheng Y, Tabbaa ZM, Khan Z et al. Epigenetic Regulation of Uterine Biology by Transcription Factor KLF11 via Post-translational Histone Deacetylation of Cytochrome p450 Metabolic Enzymes. Endocrinology. 2014-04-25 [PMID: 25076120]
• Daftary GS, Zheng Y, Tabbaa ZM et al. A Novel Role of the Sp/KLF Transcription Factor KLF11 in Arresting Progression of Endometriosis. PLoS One. 2013-03-28 [PMID: 23555910]

Bioinformatics

• Gene Symbol: KLF11
• Entrez:
  • 8462(Human)
• OMIM:
  • 603301(Human)
• Uniprot:
  • NP_003588(Human)