Kirrel2/NEPH3 Antibody (318311) [Alexa Fluor® 700]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 318311
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

Kirrel2/NEPH3 Antibody (318311) [Alexa Fluor® 700] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Kirrel2
  Gly21-Arg503
  Accession # Q6UWL6
• Specificity: Detects human and mouse Kirrel2/NEPH3 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Kirrel2/NEPH3 Antibody (318311) [Alexa Fluor® 700]

• DKFZp564A1164
• Filtrin
• FILTRINkin of IRRE-like protein 2
• kin of IRRE like 2 (Drosophila)
• Kin of irregular chiasm-like protein 2
• Kirrel2
• MGC15718
• NEPH3
• NEPH3Nephrin-like protein 3
• nephrin-like 3
• nephrin-like gene 1
• NLG1
• NLG1kin of irregular chiasm-like 2

Background

Kirrel2, also known as nephrin-like 3, nephrin-like gene 1 and filtrin, is a type I transmembrane protein belonging to the immunoglobulin superfamily. By alternative splicing, at least 5 isoforms that differ in their extracellular and/or intracellular regions have been described. Kirrel2 is expressed in the pancreas, lymph nodes, kidney glomerulus, as well as brain. The extracellular domains of human and mouse Kirrel2 share 86% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.