Kir3.1 Antibody

Images

 
Western Blot: Kir3.1 Antibody [NBP1-32958] - Analysis of Kir3.1 on A431 lysates (Lane A), H1299 lysates (Lane B) and Hela (Lane C) at a dilution of 1:1000. 30 ug of whole cell lysate loaded on 7.5% SDS PAGE gel.
Immunohistochemistry-Paraffin: Kir3.1 Antibody [NBP1-32958] - Paraffin-embedded DU145 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.7 mg/ml

Order Details

Kir3.1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human GIRK1. The exact sequence is proprietary.
Localization
Membrane, Multi-pass membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNJ3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.7 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Kir3.1 Antibody

  • G protein-activated inward rectifier potassium channel 1
  • GIRK-1
  • GIRK1Kir3.1
  • Inward rectifier K(+) channel Kir3.1
  • inward rectifier K+ channel KIR3.1
  • KGA
  • KIR3.1
  • Potassium channel, inwardly rectifying subfamily J member 3
  • potassium inwardly-rectifying channel, subfamily J, member 3

Background

FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.; Subcellular location: Membrane, Multi-pass membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KCNJ3
Entrez
Uniprot