KIR2DS2 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 650

KIR2DS2 Antibody [DyLight 650] Summary

• Immunogen: KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2. Amino Acid Squence: EPAGNRTVNSEDSDEQDH
• Specificity: KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIR2DS2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KIR2DS2 Antibody [DyLight 650]

• 183ActI
• CD158b
• CD158j
• Cl-49
• killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
• KIR2DS2
• NKAT5
• p58 KIR
• p58 NK Receptor CL-49

Background

The KIR2DS2 gene encodes a 304 amino acid long, 33 kDA killer cell immunoglobulin-like receptor 2DS2. This receptor is for HLA-C alleles but it does not prevent any activity of NK cells. The KIR2DS2 gene participates in DAP12 interactions, the innate immune system as well as the adaptive immune system, as well as immunoregulatory interactions between a lymphoid and a non-lymphoid cell. It is known to interact with genes HLA-C and TYROBP. The KIR2DS2 gene is linked to ulcerative colitis, spondylitis, anterior uveitis, diabetes, hodgkin's lymphoma, lupus, psoriatic arthritis, birdshot chorioretinopathy, and vigt-kooyanagi-harada disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KIR2DS2