KIR2DS2 Antibody [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 532

KIR2DS2 Antibody [Alexa Fluor® 532] Summary

• Immunogen: KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2. Amino Acid Squence: EPAGNRTVNSEDSDEQDH
• Specificity: KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIR2DS2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for KIR2DS2 Antibody [Alexa Fluor® 532]

• 183ActI
• CD158b
• CD158j
• Cl-49
• killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
• KIR2DS2
• NKAT5
• p58 KIR
• p58 NK Receptor CL-49

Background

The KIR2DS2 gene encodes a 304 amino acid long, 33 kDA killer cell immunoglobulin-like receptor 2DS2. This receptor is for HLA-C alleles but it does not prevent any activity of NK cells. The KIR2DS2 gene participates in DAP12 interactions, the innate immune system as well as the adaptive immune system, as well as immunoregulatory interactions between a lymphoid and a non-lymphoid cell. It is known to interact with genes HLA-C and TYROBP. The KIR2DS2 gene is linked to ulcerative colitis, spondylitis, anterior uveitis, diabetes, hodgkin's lymphoma, lupus, psoriatic arthritis, birdshot chorioretinopathy, and vigt-kooyanagi-harada disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KIR2DS2