KIF18A Antibody

Product Discontinued

KIF18A Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 848 and the C-terminus (residue 898) of human kinesin family member 18A using the numbering given in entry NP_112494.2 (GeneID 81930).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIF18A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:2000-1:10000
• Control:

  KIF18A Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KIF18A Antibody

• DKFZP434G2226
• KIF18A
• kinesin family member 18A
• kinesin-like protein KIF18A
• Marrow stromal KIF18A
• MS-KIF18A
• OK/SW-cl.108

Background

The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF18 has been demonstrated to be a microtubule depolymerase essential for chromosome alignment at the spindle equator. Alternate names for KIF18A include kinesin family member 18A, kinesin-like protein KIF18A, and DKFZP434G2226.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KIF18A Antibody (NB100-57518)(2)

Publications using NB100-57518

• Craney A, Kelly A, et al. Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation. Proc Natl Acad Sci U S A 2016-02-09 [PMID: 26811472] (WB, Human)
• Nagahara M, Nishida N, Iwatsuki M et al. Kinesin 18A expression: clinical relevance to colorectal cancer progression. Int J Cancer 2011-12-01 [PMID: 21213216]

Bioinformatics

• Gene Symbol: KIF18A
• Entrez:
  • 81930(Human)
• Uniprot:
  • NP_112494.2(Human)