KCNK4 Antibody

Western Blot: KCNK4 Antibody [NBP2-76938] - Western blot analysis of K2P4.1 on different lysates using anti-K2P4.1 antibody at 1/500 dilution.Positive control:Lane1: Mouse colon Lane2: Rat kidney

Immunohistochemistry: KCNK4 Antibody [NBP2-76938] - Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.

Flow Cytometry: KCNK4 Antibody [NBP2-76938] - Flow cytometric analysis of HepG2 cells with K2P4.1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Immunohistochemistry: KCNK4 Antibody [NBP2-76938] - Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.

Product Discontinued

KCNK4 Antibody Summary

• Immunogen: Synthetic peptide within Human KCNK4 aa 326-375 / 393. (SwissProt: Q9NYG8 Human)
• Localization: Cell membrane.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNK4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50-1:100
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500
• Theoretical MW: 43 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH7.4), 0.2% BSA, 50% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KCNK4 Antibody

• K2P4.1 potassium channel
• K2p4.1
• KCNK4
• potassium channel subfamily K member 4
• potassium channel, subfamily K, member 4
• TRAAK
• TRAAKTRAAK1
• TWIK-related arachidonic acid-stimulated potassium channel protein
• Two pore K(+) channel KT4.1
• two pore K+ channel KT4.1
• Two pore potassium channel KT4.1

Background

Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNK4