Kallikrein 11 Antibody [DyLight 550]

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 550

Kallikrein 11 Antibody [DyLight 550] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Produced in rabbits immunized with purified, recombinant Human Kallikrein 11 (Accession#: NP_006844.1; Met 1-Asn 250)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLK11
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-99572. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Kallikrein 11 Antibody [DyLight 550]

• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.4
• Hippostasin
• hK11
• Kallikrein 11
• kallikrein-related peptidase 11
• KLK11
• MGC33060
• PRSS20kallikrein-11
• Serine protease 20
• TLSPhippostasin
• Trypsin-like protease

Background

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLK11