JNK2 Antibody (252320) [Alexa Fluor® 350]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, KO
• Clone: 252320
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

JNK2 Antibody (252320) [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human JNK2 isoform 2
• Specificity: Detects human, mouse, and rat JNK2, expressed as p46 JNK (isoforms 2 and/or 3, both 382 aa) and p54 JNK (isoforms 1 and/or 4, both 424 aa) in Western blots. Does not detect recombinant JNK1 or JNK3.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Knockout Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for JNK2 Antibody (252320) [Alexa Fluor® 350]

• c-Jun kinase 2
• c-Jun N-terminal kinase 2
• EC 2.7.11
• EC 2.7.11.24
• JNK2
• JNK2A
• JNK2BETA
• JNK2JNK2ALPHA
• JNK-55
• Jun kinase
• MAP kinase 9
• MAPK 9
• MAPK9
• mitogen-activated protein kinase 9
• p54a
• p54aSAPK
• PRKM9JNK2B
• SAPK
• SAPK1 alpha
• Stress-activated protein kinase JNK2

Background

The c-Jun N-terminal kinases (JNKs) are encoded by three genes: JNK1, JNK2, and JNK3. Members of the MAPK superfamily, JNKs are activated by environmental stresses and inflammatory cytokines. JNK1, also known as SAPK1 gamma and MAPK8, is expressed as four isoforms generated by alternative splicing. JNK1 is activated by dual phosphorylation at T183 and Y185 by the MAPK kinases MKK4 and/or MKK7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.